Portal de Transparencia

Actividad investigadora:

• Artículos en revistas
  • [2019] Biosynthesis of the nitrogenase active-site cofactor precursor NifB-co in Saccharomyces cerevisiae
  • [2019] Biosynthesis of the nitrogenase active-site cofactor precursor NifB-co in Saccharomyces cerevisiae
  • [2019] Recognition motifs rather than phylogenetic origin influence the ability of targeting peptides to import nuclear-encoded recombinant proteins into rice mitochondria
  • [2018] Extreme bioengineering to meet the nitrogen challenge
  • [2018] Sequential and differential interaction of assembly factors during nitrogenase MoFe protein maturation
  • [2017] Adaptation of the GoldenBraid modular cloning system and creation of a toolkit for the expression of heterologous proteins in yeast mitochondria
  • [2017] Challenges to develop nitrogen-fixing cereals by direct nif-gene transfer (vol 225, pg 130, 2014)
  • [2017] Diversity and Functional Analysis of the FeMo-Cofactor Maturase NifB
  • [2017] Formation of Nitrogenase NifDK Tetramers in the Mitochondria of Saccharomyces cerevisiae
  • [2017] Purification and In Vitro Activity of Mitochondria Targeted Nitrogenase Cofactor Maturase NifB
  • [2017] State of the art in eukaryotic nitrogenase engineering
  • [2017] State of the art in eukaryotic nitrogenase engineering
  • [2017] State of the art in eukaryotic nitrogenase engineering
  • [2016] EXAFS reveals two Mo environments in the nitrogenase iron-molybdenum cofactor biosynthetic protein NifQ
  • [2016] Electron Paramagnetic Resonance Characterization of Three Iron-Sulfur Clusters Present in the Nitrogenase Cofactor Maturase NifB from Methanocaldococcus infernus
  • [2016] Electron Paramagnetic Resonance Characterization of Three Iron?Sulfur Clusters Present in the Nitrogenase Cofactor Maturase NifB from Methanocaldococcus infernus
  • [2016] Expression of a functional oxygen-labile nitrogenase component in the mitochondrial matrix of aerobically grown yeast
  • [2016] Hydrogen overproducing nitrogenases obtained by random mutagenesis and high-throughput screening
  • [2016] The Nitrogenase FeMo-Cofactor Precursor Formed by NifB Protein: A Diamagnetic Cluster Containing Eight Iron Atoms
  • [2015] Cyanobacterial biological nitrogen fixation as a sustainable nitrogen fertilizer for the production of microalgal oil
  • [2014] Challenges to develop nitrogen-fixing cereals by direct nif-gene transfer
  • [2013] Role of Azotobacter vinelandii FdxN in FeMo-co biosynthesis
  • [2013] Roles of Four Conserved Basic Amino Acids in a Ferredoxin-Dependent Cyanobacterial Nitrate Reductase
  • [2011] A sterile alpha-motif domain in NafY targets Apo-NifDK for iron-molybdenum cofactor delivery via a tethered domain.
  • [2011] NifB and NifEN protein levels are regulated by ClpX2 under nitrogen fixation conditions in Azotobacter vinelandii.
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• Capítulos de libros
  • [2015] BIOSYNTHESIS OF THE IRON-MOLYBDENUM COFACTOR OF NITROGENASE
  • [2015] REGULATION OF NIF GENE EXPRESSION IN AZOTOBACTER VINELANDII
  • [2014] Expression and Purification of NifB Proteins from Aerobic and Anaerobic Sources
  • [2014] Purification of O2-Sensitive metalloproteins
  • [2013] Biosynthesis of the Iron-Molybdenum Cofactor of Nitrogenase
  • [2011] Biochemistry of Mo-Nitrogenase
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• Conferencias invitadas en congresos
  • [2019] Iron Sulfur Discussion Group (2019).
  • [2017] Advances in engineering eukaryotic nitrogenase
  • [2017] Advances in engineering eukaryotic nitrogenase
  • [2017] Innovative Solutions
  • [2016] BNF Cereals Phase II
  • [2016] Biotechnological applications of nitrogenase
  • [2016] Engineering nitrogen fixation
  • [2016] Expression and Maturation of Nitrogenase Components in Mitochondria
  • [2016] Expression of Nitrogenase Component Proteins is Eukaryotes. The nitrogen nutrition of plants.
  • [2016] Nitrogenase assembly in eukaryotes
  • [2016] Optimizing H2 production by nitrogenase
  • [2016] Optimizing H2 production by nitrogenase
  • [2016] Optimizing H2 production by nitrogenase
  • [2016] Why study nitrogenase? Plant & Microbial Biology
  • [2015] Engineering nitrogenase in eukaryotes
  • [2015] NITROGENASE ASSEMBLY IN EUKARYOTES
  • [2015] NITROGENASE BIOTECHNOLOGICAL APPLICATIONS
  • [2013] Identification of an electron donor to NifB in FeMo-co biosynthesis
  • [2013] TEDxCibelesChange
  • [2012] Nitrogenase Biosynthesis: recent advances and perspectives
  • [2012] Nitrogenase biosynthesis: recent advances and perspectives
  • [2012] Quantification of Nitrogenase Structural and Biosynthetic Proteins
  • [2011] Changes in nif gene expression profiles during nitrogenase biogenesis.
  • [2011] The FdxN protein is required for the biosynthesis and activity of the NifDK and NifH nitrogenase component in Azotobacter vinelandii.
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• Cursos, seminarios y tutoriales
  • [2015] VII JORNADA CIENTÍFICA CENTRO DE BIOTECNOLOGÍA Y GENÓMICA DE PLANTAS. UPM-INIA (CBGP) 25 de Septiembre de 2015 Sala de Seminarios del CBGP, Campus de Montegancedo UPM
• Estancias y sabáticos recogidos en programas oficiales
  • [2012] Estancia en Lehrstuhl für Biologie der Mikroorganismen Ruhr-Universität
  • [2012] Estancia en el Dept. of Chemistry of the University of California at Davis
• Otras Publicaciones
  • [2018] 'Expression of mitochondria targeted NifH in Nicotiana benthamiana'
• Otros méritos
  • [2017] 2º Premio en la II edición del UPM_innovatech 2T (Technology Transfer) Challenge 2017
  • [2016] Divulgación
  • [2016] Divulgación
  • [2011] Evaluación de artículos de revistas internacionales
  • [2011] Evaluador de proyectos de investigación
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• Patentes
  • [2018] Reagents and Methods for the Expression of an Active NifB Protein and Uses Thereof.
  • [2018] Reagents and Methods for the Expression of an Active NifB Protein and Uses Thereof.
  • [2018] Reagents and methods for the expression of oxygen-sensitive proteins
  • [2013] Reagents and methods for the expression of oxygen-sensitive proteins
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• Ponencia en Congresos
  • [2017] Adaptation of the GoldenBraid modular cloning system and creation of a toolkit for the expression of mitochondrial proteins in yeast.
  • [2017] Diversity and functional analyses of NifB-cofactor maturase (NifB) for its implementation in eukaryotic systems
  • [2017] Expression of the nitrogenase iron-molybdenum cofactor maturase NifB in mitocondria of Saccharomyces cerevisiae.
  • [2017] High-throughput screening of hydrogen overproducing photosynthetic bacteria
  • [2016] Engineering a hydrogen biosensor: selection of overproducing nitrogenase variants for biohydrogen production
  • [2016] Expression of a functional oxygen-labile nitrogenase component in the mitocondrial matrix of aerobically grown yeast.
  • [2016] Molybdenum metabolism in Azotobacter vinelandii
  • [2015] A NOVEL METHOD TO ISOLATE NATIVE NIFB-COFACTOR
  • [2015] ENGINEERING A HYDROGEN BIOSENSOR: SELECTION OF OVERPRODUCING NITROGENASE VARIANTS FOR BIOHYDROGEN PRODUCTION
  • [2015] NifQ and NifO are essential to express nitrogenase activity in the presence of nitrate in Azotobacter vinelandii
  • [2014] Engineering nitrogen fixation in eukaryots
  • [2014] Generation of mature NifH variants independent of NifM function
  • [2014] Nitrogenase and nitrate reductase activities of Azotobacter vinelandii nifO and nifQ mutants growing diazotrophically in the presence of nitrate
  • [2014] The NifX-like domain found in Klebsiella oxytocaNifB is not required for NifB-co synthesis
  • [2013] Engineering a hydrogen biosensor in the nitrogen-fixing strain Rhodobacter capsulatus
  • [2013] Temporal profile of nif gene expression in Azotobacter vinelandii: effect of nifA mutation
  • [2013] The FdxN protein is required for the biosynthesis and activity of the NifDK nitrogenase components in Azotobacter vinelandii
  • [2013] Towards the optimization of hydrogen production by nitrogenase: In vitro directed evolution of Rhodobacter capsulatus molybdenum nitrogenase
  • [2013] Two-Hybrid System in the nitrogen-fixing bacterium Azotobacter vinelandii
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• Premios
  • [2017] 2º Premio en la II edición del UPM_innovatech 2T (Technology Transfer) Challenge 2017
• Proyectos de I+D+i
  • [2019] CHARGEREEN
  • [2019] SymBioM: Laboratorio de Biología de Sistemas y Modelización Biológica del CBGP (UPM-INIA)
  • [2018] : Sistema de alto rendimiento para la producción fotobiológica de hidrógeno
  • [2018] FIXIT: Nuevos Paradigmas en Biogenesis de Nitrogenasa
  • [2018] SUBPROGRAMA ESTATAL DE FORTALECIMIENTO INSTITUCIONAL. CENTROS DE EXCELENCIA SEVERO OCHOA Y UNIDADES DE EXCELENCIA MARÍA DE MAEZTU
  • [2017] BNF CEREALS PHASE II
  • [2017] BNF CEREALS PHASE II
  • [2016] BNF CEREALS PHASE II
  • [2016] BNF CEREALS: BNF CEREALS PHASE II
  • [2015] BIO-N2: Aplicaciones biotecnológicas de la nitrogenasa
  • [2015] PlantFrontiers: Nuevas fronteras de la biología de plantas
  • [2015] TOWARDS THE OPTIMIZATION OF HYDROGEN PRODUCTION BY NITROGENASE - TOHPN
  • [2013] BIOSISTESIS DEL COFACTOR DE HIERRO Y MOLIBDENO DE LA NITROGENASA
  • [2012] AZOTOBACTER VINELANDII COMO BIOFACTORÍA PARA LA PRODUCCIÓN DE HIDRÓGENO
  • [2012] BIOSISTESIS DEL COFACTOR DE HIERRO Y MOLIBDENO DE LA NITROGENASA
  • [2012] ENGINEERING NITROGEN FIXATION IN MITOCHONDRIA
  • [2012] Ingineering nitrogen fixation in mitochondria
  • [2011] AZOTOBACTER VINELANDII COMO BIOFACTORÍA PARA LA PRODUCCIÓN DE HIDRÓGENO
  • [2011] BIOSISTESIS DEL COFACTOR DE HIERRO Y MOLIBDENO DE LA NITROGENASA
  • [2011] ENGINEERING NITROGEN FIXATION IN MITOCHONDRIA
  • [2011] NFIX: Engineering nitrogen fixation in mitochondria
  • [2011] TOHPN: Towards the optimization of hydrogen production by nitrogenase
  • [2011] TOHPN: Towards the optimization of hydrogen production by nitrogenase
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• Responsabilidades
  • [2019] Miembros del equipo directivo del CBGP
  • [2018] Miembros del equipo directivo del CBGP
  • [2017] Miembros del equipo directivo del CBGP
  • [2016] Commitee Member
  • [2016] Miembro del External Advisory Board
  • [2016] Steering Committee Member
  • [2016] Steering Committee Member
  • [2016] Subdirector
  • [2016] Subdirector del Centro de Biotecnología y Genómica de Plantas
  • [2015] Investigador Responsable de Grupo de Investigación UPM
  • [2015] XV CONGRESO DE LA SOCIEDAD ESPAÑOLA DE FIJACION DE NITROGENO (SEFIN)
  • [2013] Consejo Científico Asesor del CBGP
  • [2012] International Scientific Advisory Board de la European Nitrogen Fixation Conference
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• Tesis Doctorales
  • [2019] Molybdenum metabolism in Azotobacter vinelandii and its biotechnological applications
  • [2018] Synthetic biology tools for the study of relevant factors in the control of transgene
  • [2017] Caracterización de una nueva proteína hipertermófila NifB y su papel en el mecanismo de síntesis de NifB-co, precursor del grupo metálico de FeMo-co.
  • [2017] Caracterización de una nueva proteína hipertermófila NifB y su papel en el mecanismo de síntesis de NifB-co, precursor del grupo metálico de FeMo-co.
  • [2017] Characterization of a new hyperthermophilic NifB protein and its role in the mechanism of synthesis of NifB-co, a precursor of the metal cage of FeMo-co
  • [2014] AZOTOBACTER VINELANDII NITROGENASE: KINETICS OF NIF GENE EXPRESSION AND INSIGHTS INTO THE ROLES OF FDXN AND NIFQ IN FEMO-CO BIOSYNTHESIS
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