Portal de Transparencia

Actividad investigadora:

• Artículos en revistas
  • [2019] A new variant (c.1A > G) in LDLRAP1 causing autosomal recessive hypercholesterolemia: Characterization of the defect and response to PCSK9 inhibition
  • [2018] Bone Marrow Hematopoietic Connexin 43 Is Required for Mitotransfer and AMPK Dependent Mesenchymal Microenvironment Regeneration after Irradiation
  • [2018] Comparison of the effects of post-spinning drawing and wet stretching on regenerated silk fibers produced through straining flow spinning
  • [2018] Connexin-43 Is a Negative Regulator of Mitochondrial Fission, Mitophagy and Apoptosis of Dividing Hematopoietic Stem Cells through the Drp1-Pink1 Axis
  • [2018] Cortical Reshaping and Functional Recovery Induced by Silk Fibroin Hydrogels-Encapsulated Stem Cells Implanted in Stroke Animals
  • [2018] Directional coupling of oligodendrocyte connexin-47 and astrocyte connexin-43 gap junctions
  • [2018] Extreme events in epileptic EEG of rodents after ischemic stroke
  • [2018] Hydrogels-Assisted Cell Engraftment for Repairing the Stroke-Damaged Brain: Chimera or Reality
  • [2016] Safety and tolerability of silk fibroin hydrogels implanted into the mouse brain
  • [2015] A NOVEL MUTATION (CYS352SER) IN THE LDLR GENE IN THE SPANISH POPULATION
  • [2015] Connexins: Intercellular Signal Transmitters in Lymphohematopoietic Tissues.
  • [2015] Long-term dynamics of somatosensory activity in a stroke model of distal middle cerebral artery oclussion
  • [2015] Myelinating oligodendrocytes generated by direct cell reprogramming from adult rat adipose tissue
  • [2014] Inhibition of connexin 36 hemichannels by glucose contributes to the stimulation of insulin secretion
  • [2014] p62 Is Required for Stem Cell/Progenitor Retention through Inhibition of IKK/NF-kappa B/Ccl4 Signaling at the Bone Marrow Macrophage-Osteoblast Niche
  • [2013] Regulation of connexin hemichannel activity by membrane potential and the extracellular calcium in health and disease
  • [2013] Role of Connexin 32 Hemichannels in the Release of ATP from Peripheral Nerves
  • [2012] Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors
  • [2012] Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells
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• Conferencias invitadas en congresos
  • [2011] A common mechanism of defective channel trafficking underlying DFNA2 hearing loss result in different cell surface expression levels of KCNQ4 mutants
  • [2011] A missense mutation (p.G132A) of neuronal gap junction connexin-36 in a familiar form of juvenile myoclonic epilepsy that impairs electrical coupling.
  • [2011] Interaction between connexin-26 and connexin-30 to control ATP release in xenopus laevis oocytes
  • [2011] Molecular bases for the rectifying properties of heterotypic oligodendrocyte connexin-47 and astrocyte connexin-43 junctions
  • [2011] Normal and pathological astrocyte-oligodendrocyte coupling
  • [2011] Properties of connexin-47 mutant channels causing dysmyelination (Oral). 3rd Spanish Meeting of Ionic Channels (RECI)
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• Cursos, seminarios y tutoriales
  • [2018] Nuevos abordajes para restaurar la funcionalidad del tejido cerebral dañado
• Otros méritos
  • [2017] MEDIOS DE COMUNICACIÓN: Fibroína, un biomaterial para reparar daño cerebral
  • [2017] Medios de comunicación: Estudio de la UPM avala uso de un biomaterial para reparar daños cerebrales
• Ponencia en Congresos
  • [2018] Bone Marrow Hematopoietic Connexin 43 Is Required for Mitotransfer and AMPK Dependent Mesenchymal Microenvironment Regeneration after Irradiation
  • [2018] Connexin-43 Is a Negative Regulator of Mitochondrial Fission, Mitophagy and Apoptosis of Dividing Hematopoietic Stem Cells through the Drp1-Pink1 A
  • [2017] Connexin-43 (Cx43) Regulates Mitochondrial Dynamics through Macroscopic Autophagy in Dividing Hematopoietic Stem Cells
  • [2017] Connexin-43 (Cx43) Regulates Mitochondrial Transfer from Hematopoietic Stem and Progenitor Cells to Bone Marrow Stromal Cells via AMPK and ATP signaling.
  • [2015] Mechanism of demyelination by connexin-43 mutations associated with oculodentodigital dysplasia
  • [2015] Connexin-36 protects against suddent infant death syndrome
  • [2015] Long-term dynamics of somatosensory activity in a stroke model of distal middle cerebral artery occlusion
  • [2015] Mathematical modeling of neuronal connexin-36 channels
  • [2015] Molecular determinats for the intercellular diffusion barrier between oligodendrocytes and astrocyte
  • [2015] Myelinating oligodendrocytes generated by direct cell reprogramming from adult rat adipose tissue
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• Proyectos de I+D+i
  • [2018] CENTRO TECNOLOGICO PARA EL ESTUDIO Y TRATAMIENTO INTEGRADO DE LOS DESORDENES NEUROLOGICOS
  • [2018] EIT Health Product-Market Fit 2018: EIT Health Product-Market Fit 2018
  • [2018] miniQ: miniQ
  • [2017] EIT Health Product - Market Fit 2017: EIT Health Product/Market Fit 2017
  • [2017] MiniQ-2017: Optimising drug treatment among older people through a patient centered web based decision support
  • [2016] SILKBRAIN: Desarrollo de nuevos biomateriales de fibroína de seda para regeneración cerebral
  • [2015] : Animalario del Centro de Tecnología Biomédica y Centros del Campus Montegancedo de la UPM
  • [2015] CONSORCIO NEUROTEC-PROGRAMA INTEGRAL DE INGENIERÍA BIOMÉDICA PARA EL DESARROLLO DE TÉCNICAS DIAGNÓSTICAS Y TERAPÉUTICAS EN ENFERMEDADES NEUROLÓGICAS
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• Tesis Doctorales
  • [2017] TERAPIA CELULAR ASISTIDA POR HIDROGELES DE FIBROÍNA EN UN MODELO EXPERIMENTAL DE ICTUS CEREBRAL